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Molecular Biology

STEM PROGRAM

Description

The Molecular Biology for Pharmacists is an intensive, two-month program designed to bridge the gap between pharmacy practice, research, and molecular biology. Tailored specifically for Pharm.D. and relevant clinical degree students, graduates, and research professionals, this program offers a comprehensive blend of theoretical knowledge and practical laboratory training.

Through 20 sessions and hands-on and/or virtual lab work, scholars will gain a deeper understanding of molecular mechanisms in drug action, precision medicine, and modern molecular techniques essential for advanced clinical practice and research.

This program is ideal for those looking to expand their expertise in Molecular Biology, Pharmacogenomics, MB techniques, molecular diagnostics, and related clinical lectures making them more competitive in clinical and research roles.

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Affiliations

DNA Labs – A Centre for Applied Sciences (DLCAS), Dehradun, Uttarakhand is an ISO 9001:2015 Certified, NABL Accredited, ICMR Approved, and LSSSDC Certified Laboratoryworking in the field of Diagnostics, Science Education, and Research.

This collaborative program aims to bridge the gap between academic knowledge and practical industry skills. By combining Pharmscape’s educational framework with DLCAS’s advanced lab facilities, participants can gain both theoretical knowledge and hands-on experience, making them well-prepared for careers in molecular biology, diagnostics, and research.

Why to Enroll?

Features and Benefits

Program

Our consultants, including researchers, clinicians, and industry experts in molecular biology, pharmacogenomics, and clinical research, lead sessions with extensive theoretical and practical expertise in molecular biology and its pharmaceutical applications.

Theory | Online

Unit 1.1: DNA, RNA, and Protein Synthesis – An Overview

This session provides an introduction to the central dogma of molecular biology, covering the structure and function of DNA, RNA, and proteins. It highlights the processes of transcription and translation, emphasizing how genetic information is converted into functional proteins that drive cellular processes.

Unit 1.2: Gene Structure, Function, and Regulation

Dive deeper into gene architecture, exploring the roles of exons, introns, promoters, and enhancers. This session covers the mechanisms of gene expression regulation, including transcription factors, epigenetic modifications, and post-transcriptional control, crucial for understanding how genes are turned on and off in response to various stimuli.

Unit 2.1: Polymerase Chain Reaction (PCR) and Its Applications

PCR is a fundamental tool in molecular biology and drug development. This session covers the principles of PCR, its various types (e.g., qPCR, RT-PCR), and its applications in detecting genetic mutations, pathogen identification, and personalized medicine.

Unit 2.2: CRISPR-Cas9 Gene Editing: Principles and Uses in Medicine

CRISPR-Cas9 technology has revolutionized genetic engineering. This session introduces the basic concepts of CRISPR, how it works, and its applications in gene therapy, drug development, and correcting genetic disorders.

Unit  3.1: Genetic Polymorphisms and Their Impact on Drug Response

This session explores the role of genetic polymorphisms in drug metabolism and efficacy. Understanding these variations can help optimize drug dosing, reduce adverse effects, and improve therapeutic outcomes.

Unit 3.2: Implementing Pharmacogenomic Data in Clinical Practice

Learn how to integrate pharmacogenomic data into everyday clinical practice. This session covers case studies, clinical guidelines, and the use of decision support tools to tailor drug therapy based on a patient’s genetic makeup.

Unit 4.1: Molecular Mechanisms in Cancer Development and Progression

Cancer is a disease of altered molecular pathways. This session examines the genetic and epigenetic changes that lead to oncogenesis, including mutations in tumor suppressor genes and oncogenes, and how these insights guide targeted cancer therapies.

Unit 4.2: Understanding the Molecular Biology of Infectious Diseases

Explore the molecular interactions between pathogens and host cells, focusing on how these interactions lead to disease. This session covers viral replication, bacterial gene regulation, and emerging molecular targets for combating infectious diseases.

Unit 5.1: The Science Behind Monoclonal Antibodies and Biologics

Biologics represent a rapidly growing class of therapeutics. This session covers the development, structure, and function of monoclonal antibodies and other biologics, with a focus on their mechanisms of action and therapeutic applications.

Unit 5.2: Challenges and Opportunities in Developing Biosimilars

As patents for biologics expire, biosimilars are becoming more important. This session discusses the regulatory, clinical, and manufacturing challenges of developing biosimilars, as well as their potential to reduce healthcare costs while maintaining therapeutic efficacy.

Unit 6.1: Principles of Gene Therapy and Its Applications in Medicine

Gene therapy holds the promise of curing genetic diseases by directly modifying the DNA of affected cells. This session explores the principles of gene therapy, including delivery methods, safety considerations, and current applications in treating genetic disorders.

Unit 6.2: Advances in RNA-Based Therapeutics (siRNA, mRNA)

RNA-based therapies, such as siRNA and mRNA vaccines, represent cutting-edge molecular medicine. This session covers the development, mechanism, and therapeutic applications of RNA-based drugs, with a focus on recent advancements in treating viral infections and genetic diseases.

Unit 7.1: Next-Generation Sequencing (NGS) and Its Clinical Applications

Next-Generation Sequencing (NGS) has transformed genomics. This session provides an overview of NGS technology, its workflow, and its applications in diagnosing genetic disorders, guiding cancer treatment, and detecting infectious agents.

Unit 7.2: Molecular Biomarkers in Disease Diagnosis and Prognosis

Molecular biomarkers are critical for early disease detection and monitoring treatment response. This session covers the discovery, validation, and clinical application of molecular biomarkers in cancer, cardiovascular diseases, and other conditions.

Unit 8.1: The Molecular Biology of Stem Cells

Stem cells hold the potential to regenerate damaged tissues and treat various diseases. This session covers the biology of stem cells, including their properties, differentiation pathways, and therapeutic applications in regenerative medicine.

Unit 8.2: Therapeutic Applications of Stem Cells in Regenerative Medicine

Explore how stem cells are being used in clinical applications, from treating neurodegenerative diseases to regenerating heart tissue. This session also discusses the challenges and ethical considerations in stem cell research and therapy.

Unit 9.1: Receptor Signaling Pathways and Drug Targets

Understanding receptor signaling is crucial for developing targeted therapies. This session covers key signaling pathways, such as GPCRs, RTKs, and ion channels, and their relevance as drug targets in treating diseases.

Unit 9.2: Molecular Mechanisms of Drug Resistance

Drug resistance is a major challenge in treating diseases like cancer and infections. This session examines the molecular mechanisms behind drug resistance, including genetic mutations, efflux pumps, and epigenetic modifications, and strategies to overcome resistance.

Unit 10.1: Ethical Considerations in Genetic Research and Therapy

The advancement of molecular medicine raises significant ethical questions. This session explores the ethical implications of genetic research, gene therapy, and CRISPR-based editing, including issues of consent, privacy, and the potential for genetic discrimination.

Unit 10.2: Regulatory Pathways for Molecular and Gene-Based Therapies

Developing molecular therapies requires navigating complex regulatory frameworks. This session provides an overview of the regulatory processes for molecular and gene-based therapies, focusing on approval pathways, clinical trial design, and post-marketing surveillance.

Laboratory | Virtual or In-Person Internship

  • Objective: Teach participants the fundamentals of extracting and purifying high-quality DNA from various biological samples (e.g., blood, saliva, tissue).
  • Lab Focus: Hands-on experience in DNA extraction protocols, followed by assessing DNA purity and concentration using spectrophotometry or gel electrophoresis.
  • Objective: Train participants in the principles and applications of PCR, including DNA amplification and quantification.
  • Lab Focus: Setting up a PCR reaction, understanding the thermocycling process, and analyzing results using gel electrophoresis or real-time PCR.
  • Objective: Introduce participants to CRISPR-Cas9 technology, focusing on its use in gene editing for therapeutic purposes.
  • Lab Focus: Performing gene knockout or insertion in a cell line using CRISPR-Cas9, followed by validation of gene editing through sequencing or PCR.
  • Objective: Teach participants the steps involved in preparing samples for NGS and the basics of analyzing sequencing data.
  • Lab Focus: DNA/RNA extraction, library preparation, and an introduction to bioinformatics tools for sequence alignment and variant analysis.
  • Objective: Provide hands-on experience with ELISA for detecting and quantifying proteins, such as biomarkers or therapeutic antibodies.
  • Lab Focus: Setting up and conducting an ELISA, analyzing results, and understanding the sensitivity and specificity of the assay.
  • Objective: Train participants using flow cytometry to analyze cell populations, such as immune cells, based on molecular markers.
  • Lab Focus: Stain cells with fluorescent antibodies, run samples on a flow cytometer, and interpret data on cell population and marker expression.

As the Program Director of Molecular Biology, I’m excited to collaborate with Pharmscape in sharing interdisciplinary knowledge with their global audience. It’s rewarding to see participants’ enthusiasm and the impact on their professional growth, shaping the next generation of scientists and researchers. I’m thrilled to contribute to their journey.

Program Director – Scientist and Head, DNA Labs

LABORATORY INSIGHTS

Gallery

FEE

Choose the Best Fit Plan.

Starter

Online Lecture (STEM)

₹ 2,999

20 Live Sessions

Access to recordings

Assessment | Quizzes

Certificate of Program Completion (Hard Copy)

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Best Choice

STEM + Virtual Internship

₹ 8,999

20 Live Sessions

Access to recordings​

Assessment | Quizzes

Certificate of Program Completion (Hard Copy)

Virtual Internship Completion (Hard Copy)

e - textbooks + e - Laboratory Manual

Pharmscape e-kit

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ADVANCED

STEM + On-Site Internship

₹ 14,999

20 Live Sessions

Access to recordings​

Assessment | Quizzes

Certificate of Program Completion (Hard Copy)

Internship Completion (Hard Copy)

Text Books + Laboratory Manual

Pharmscape kit

Study Resources